Two Cases of Essential Purpura Hæmorrhagica Six Years after Splenectomy

Treatment of Purpura Hæmorrhagica

Report of two unrelated cases of Familial Thrombotic Thrombocytopeic Purpura

Thrombotic Thrombocytopenic Purpura (TTP) is a rare microangiopathic disorder characterised by the pentad of microangiopathic hemolytic anemia, thrombocytopenic purpura, neurologic abnormalities, fever, and renal disease. Decreased production and/or activity of ADAMTS13 is the cause of this disorder. ADAMTS13 is a metalloproteinase which is responsible of the cleavage of high weight multimers o...

Late recurrence of thrombotic thrombocytopenic purpura after splenectomy.

The second patient was investigated by his G.P. at the age of 34 in 1952. He had been married for 14 vears with no children. A phvsical examination was normal, as was his sexual function. No abnormalities had been found when his wife was investigated in 1946. In 1968 he was referred from his G.P. with a three-week history of diarrhoea. Faecal fats were 22 g/dy, and jejunal biopsy showed subtota...

Late Results After Splenectomy in Adult Idiopathic Thrombocytopenic Purpura

BACKGROUND We performed a retrospective study on patients with idiopathic thrombocytopenic purpura (ITP) to evaluate the response to splenectomy in relation to preoperative platelet count. MATERIALS AND METHODS Two groups of patients operated on with laparoscopic or open splenectomy for ITP, with a platelet count ≤30,000/μL (study group: 22 patients) and >30,000/μL (control group: 18 patients...

Intrahepatic splenosis after splenectomy performed for idiopathic thrombocytopenic purpura.

The term splenosis describes autotransplantation or implantation of ectopic splenic tissue within the abdominal cavity or in any other unusual body compartment. In addition to the diagnostic dilemma it causes, splenosis may also lead to persistence or recurrence of hematologic dysfunctions by its preserved immune activity especially in cases of splenectomy due to hematologic indications. Herein...